ROS signaling during granzyme B-mediated apoptosis
نویسندگان
چکیده
منابع مشابه
ROS signaling during granzyme B-mediated apoptosis
Reactive oxygen species (ROS) are involved in cell signaling, aging, and death and play a role in carcinogenesis. However, whether ROS are bystanders or active effectors of apoptosis was unclear until recently. New evidence shows that the killer lymphocyte protease granzyme B activates a conserved biochemical pathway centered on respiratory chain disruption to trigger mitocentric ROS-dependent ...
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ژورنال
عنوان ژورنال: Molecular & Cellular Oncology
سال: 2015
ISSN: 2372-3556
DOI: 10.4161/23723556.2014.992639